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3e5 of HeLa cells were co-incubated with 50 nM Cy3-labeled LNPs-siRNA in the presence or absence of 3 μg/mL Human Apolipoprotein E / APOE3 Protein, Tag Free (MALS verified) (ACRO Biosystems, Cat. No. APE-H5216), washed and analyzed with FACS. PE signal was used to evaluate the expression of Cy3+ HeLa cells (Routinely tested).
3e5 of HeLa cells were co-incubated with 50 nM Cy3-labeled LNPs-siRNA in the presence or absence of 1 μg/mL Biotinylated Human APOE4, His,Avitag (Cat. No. APE-H52E7), washed and analyzed with FACS. PE signal was used to evaluate the expression of Cy3+ HeLa cells (Routinely tested).
Cynomolgus TREM2, His Tag (Cat. No. TR2-C52H3) immobilized on CM5 Chip can bind Cynomolgus Apolipoprotein E Protein, His Tag (Cat. No. APE-C52H7) with an affinity constant of 7.78 μM as determined in a SPR assay (Biacore 8K) (QC tested).
Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
---|---|---|---|---|---|
CN-105 | CN-105 | Phase 2 Clinical | Aegiscn Llc | Cerebral Hemorrhage; Stroke | Details |
LX-1001 | LX-1001 | Phase 2 Clinical | LEXEO Therapeutics | Alzheimer Disease | Details |
CN-105 | CN-105 | Phase 2 Clinical | Aegiscn Llc | Cerebral Hemorrhage; Stroke | Details |
LX-1001 | LX-1001 | Phase 2 Clinical | LEXEO Therapeutics | Alzheimer Disease | Details |
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